| Item Type | Name |
|
Concept
|
Acute Disease
|
|
Concept
|
Actins
|
|
Concept
|
Action Potentials
|
|
Concept
|
Age Factors
|
|
Concept
|
Adenosine
|
|
Concept
|
Arrhythmias, Cardiac
|
|
Concept
|
Algorithms
|
|
Concept
|
Alleles
|
|
Concept
|
Energy Intake
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
Animals
|
|
Concept
|
Anura
|
|
Concept
|
Chromosomes, Human, Pair 2
|
|
Concept
|
Chromosomes, Human, Pair 8
|
|
Concept
|
Computer Graphics
|
|
Concept
|
Computer Simulation
|
|
Concept
|
Asthma
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Movement
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Atrial Fibrillation
|
|
Concept
|
Atrioventricular Node
|
|
Concept
|
Pan troglodytes
|
|
Concept
|
Binding Sites
|
|
Concept
|
Blood Glucose
|
|
Concept
|
Chromosomes, Human, Pair 15
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Genes, Homeobox
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
DNA, Mitochondrial
|
|
Concept
|
Diabetic Nephropathies
|
|
Concept
|
Diet
|
|
Concept
|
Injections, Intraperitoneal
|
|
Concept
|
Insulin
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
DNA, Bacterial
|
|
Concept
|
Leukemia
|
|
Concept
|
Fathers
|
|
Concept
|
Economics
|
|
Concept
|
Fishes
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Introns
|
|
Concept
|
Electrocardiography
|
|
Concept
|
Genes
|
|
Concept
|
Obesity
|
|
Concept
|
Heart
|
|
Concept
|
Heart Diseases
|
|
Concept
|
Heart Failure
|
|
Concept
|
Heart Septal Defects, Atrial
|
|
Concept
|
Heart Ventricles
|
|
Concept
|
Embryo, Mammalian
|
|
Concept
|
Energy Metabolism
|
|
Concept
|
Endocardium
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Gene Amplification
|
|
Concept
|
Multigene Family
|
|
Concept
|
Heart Atria
|
|
Concept
|
Lactoylglutathione Lyase
|
|
Concept
|
Hyperplasia
|
|
Concept
|
Microfilament Proteins
|
|
Concept
|
Mammals
|
|
Concept
|
Myocardial Infarction
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Models, Genetic
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Platelet-Derived Growth Factor
|
|
Concept
|
Markov Chains
|
|
Concept
|
Extracellular Matrix
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
Intellectual Disability
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Myocardial Contraction
|
|
Concept
|
Health Promotion
|
|
Concept
|
Rhabdomyosarcoma
|
|
Concept
|
Rhinovirus
|
|
Concept
|
RNA, Fungal
|
|
Concept
|
Ion Channels
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Muscle Proteins
|
|
Concept
|
Feeding Behavior
|
|
Concept
|
Pregnancy Outcome
|
|
Concept
|
Proinsulin
|
|
Concept
|
Prostatic Neoplasms
|
|
Concept
|
Protein Binding
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Proteins
|
|
Concept
|
Glucose Tolerance Test
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Heart Defects, Congenital
|
|
Concept
|
Repressor Proteins
|
|
Concept
|
Risk Factors
|
|
Concept
|
Xenopus
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Sialoglycoproteins
|
|
Concept
|
Humans
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Tretinoin
|
|
Concept
|
Software
|
|
Concept
|
Syndrome
|
|
Concept
|
Germ-Line Mutation
|
|
Concept
|
Sodium Channels
|
|
Concept
|
Oncogene Proteins
|
|
Concept
|
Oncogene Proteins, Fusion
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Insulin-Like Growth Factor Binding Protein 6
|
|
Concept
|
Genes, Essential
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Gene Duplication
|
|
Concept
|
Respiratory Mucosa
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Chromosomes, Artificial, Bacterial
|
|
Concept
|
S Phase
|
|
Concept
|
Prosencephalon
|
|
Concept
|
G1 Phase
|
|
Concept
|
Mitochondria
|
|
Concept
|
Weight Gain
|
|
Concept
|
Leukemia, Biphenotypic, Acute
|
|
Concept
|
Gene Expression
|
|
Concept
|
Comorbidity
|
|
Concept
|
Chromosomes, Mammalian
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Proto-Oncogene Proteins c-myc
|
|
Concept
|
Myocardium
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Lower Extremity Deformities, Congenital
|
|
Concept
|
In Situ Hybridization
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Connexins
|
|
Concept
|
Methylation
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Cardiomyopathies
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Point Mutation
|
|
Concept
|
Fetal Development
|
|
Concept
|
Strongylocentrotus purpuratus
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Disease Progression
|
|
Concept
|
Muscle, Skeletal
|
|
Concept
|
ras Proteins
|
|
Concept
|
Glucose Intolerance
|
|
Concept
|
Desmoplakins
|
|
Concept
|
Maf Transcription Factors, Large
|
|
Concept
|
Hepatocyte Nuclear Factor 1-alpha
|
|
Concept
|
Versicans
|
|
Concept
|
Drosophila Proteins
|
|
Concept
|
CpG Islands
|
|
Concept
|
Myosin Heavy Chains
|
|
Concept
|
Receptor, ErbB-3
|
|
Concept
|
GABA-A Receptor Agonists
|
|
Concept
|
B7-H1 Antigen
|
|
Concept
|
Embryonic Development
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
Chromatin Assembly and Disassembly
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
Response Elements
|
|
Concept
|
Perinatal Care
|
|
Concept
|
Internet
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
ras GTPase-Activating Proteins
|
|
Concept
|
Amino Acid Motifs
|
|
Concept
|
DNA, Intergenic
|
|
Concept
|
Databases, Genetic
|
|
Concept
|
Myocytes, Cardiac
|
|
Concept
|
Prenatal Exposure Delayed Effects
|
|
Concept
|
Animals, Genetically Modified
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Mice
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Hedgehog Proteins
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Mechanotransduction, Cellular
|
|
Concept
|
Sleep Wake Disorders
|
|
Concept
|
Xylella
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Intra-Abdominal Fat
|
|
Concept
|
Adiposity
|
|
Concept
|
GATA6 Transcription Factor
|
|
Concept
|
Rats
|
|
Concept
|
Transposition of Great Vessels
|
|
Concept
|
Static Electricity
|
|
Concept
|
Inhibitor of Differentiation Protein 2
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
Sleep
|
|
Concept
|
Osteopontin
|
|
Concept
|
Insulin-Secreting Cells
|
|
Concept
|
Regulatory Elements, Transcriptional
|
|
Concept
|
Zebrafish
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Protein Interaction Domains and Motifs
|
|
Concept
|
Cyclins
|
|
Concept
|
Thyroxine-Binding Globulin
|
|
Concept
|
Trophoblasts
|
|
Concept
|
Vertebrates
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Tunica Intima
|
|
Concept
|
Gene Expression Regulation, Leukemic
|
|
Concept
|
Receptor, ErbB-2
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Short Interspersed Nucleotide Elements
|
|
Concept
|
T-Box Domain Proteins
|
|
Concept
|
Tetraodontiformes
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Cardiac Myosins
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Body Patterning
|
|
Concept
|
Untranslated Regions
|
|
Concept
|
Polypyrimidine Tract-Binding Protein
|
|
Concept
|
DNA Sequence, Unstable
|
|
Concept
|
Takifugu
|
|
Concept
|
Synteny
|
|
Concept
|
Transcription Factor 7-Like 2 Protein
|
|
Concept
|
gamma Catenin
|
|
Concept
|
Activating Transcription Factor 4
|
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
|
Concept
|
Proglucagon
|
|
Concept
|
Transcriptome
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Haploinsufficiency
|
|
Concept
|
Upper Extremity Deformities, Congenital
|
|
Concept
|
LIM-Homeodomain Proteins
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Premature Birth
|
|
Concept
|
T Cell Transcription Factor 1
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Pore Forming Cytotoxic Proteins
|
|
Concept
|
Cyclin D2
|
|
Concept
|
Induced Pluripotent Stem Cells
|
|
Concept
|
Epigenomics
|
|
Concept
|
Diet, High-Fat
|
|
Concept
|
Calcium-Binding Proteins
|
|
Concept
|
Cell Line
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Chickens
|
|
Concept
|
Chromatin
|
|
Concept
|
Chromosome Aberrations
|
|
Concept
|
Chromosomes, Human, Pair 16
|
|
Concept
|
Cytoskeletal Proteins
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Dietary Fats
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
DNA Helicases
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Food Preferences
|
|
Concept
|
Gestational Age
|
|
Concept
|
Heart Conduction System
|
|
Concept
|
Heart Rate
|
|
Concept
|
Lymphocytes
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Models, Biological
|
|
Concept
|
Neoplasm Proteins
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Histone-Lysine N-Methyltransferase
|
|
Concept
|
Proteinuria
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Conserved Sequence
|
|
Concept
|
Coculture Techniques
|
|
Concept
|
Computational Biology
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Expressed Sequence Tags
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
Genomics
|
|
Concept
|
Quantitative Trait Loci
|
|
Concept
|
Gastrointestinal Tract
|
|
Concept
|
Molecular Dynamics Simulation
|
|
Concept
|
Genetic Loci
|
|
Academic Article
|
Gene structure and chromosomal mapping of the rat smooth muscle calponin gene.
|
|
Academic Article
|
Automated construction of high-density comparative maps between rat, human, and mouse.
|
|
Academic Article
|
Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation.
|
|
Academic Article
|
Scanning human gene deserts for long-range enhancers.
|
|
Academic Article
|
Initial characterization of a rat model of diabetic nephropathy.
|
|
Academic Article
|
Comparative genomics at the vertebrate extremes.
|
|
Academic Article
|
Identifying synonymous regulatory elements in vertebrate genomes.
|
|
Academic Article
|
Evolution and functional classification of vertebrate gene deserts.
|
|
Academic Article
|
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.
|
|
Academic Article
|
In vivo characterization of a vertebrate ultraconserved enhancer.
|
|
Academic Article
|
In vivo enhancer analysis of human conserved non-coding sequences.
|
|
Academic Article
|
ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes.
|
|
Academic Article
|
Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat.
|
|
Academic Article
|
An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer.
|
|
Academic Article
|
Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers.
|
|
Academic Article
|
Genome-wide maps of transcription regulatory elements.
|
|
Academic Article
|
Genome-wide discovery of human heart enhancers.
|
|
Academic Article
|
Genome-wide identification of conserved regulatory function in diverged sequences.
|
|
Academic Article
|
Transcriptional enhancers in development and disease.
|
|
Academic Article
|
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.
|
|
Academic Article
|
Modulation ofTcf7l2 expression alters behavior in mice.
|
|
Academic Article
|
An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.
|
|
Academic Article
|
Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer.
|
|
Academic Article
|
TBX5 drives Scn5a expression to regulate cardiac conduction system function.
|
|
Academic Article
|
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function.
|
|
Academic Article
|
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.
|
|
Academic Article
|
A fine-scale chimpanzee genetic map from population sequencing.
|
|
Academic Article
|
Predicting tissue-specific enhancers in the human genome.
|
|
Academic Article
|
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism.
|
|
Academic Article
|
Appendage expression driven by the Hoxd Global Control Region is an ancient gnathostome feature.
|
|
Academic Article
|
Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.
|
|
Academic Article
|
Journal club. A human geneticist explores the ways that genes are regulated.
|
|
Academic Article
|
The emerging genetic landscape underlying cardiac conduction system function.
|
|
Academic Article
|
Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome.
|
|
Academic Article
|
FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.
|
|
Academic Article
|
Exploiting human--fish genome comparisons for deciphering gene regulation.
|
|
Academic Article
|
In vitro scan for enhancers at the TCF7L2 locus.
|
|
Academic Article
|
TCF7L2 and glucose metabolism: time to look beyond the pancreas.
|
|
Academic Article
|
A novel mechanism of inherited TBG deficiency: mutation in a liver-specific enhancer.
|
|
Academic Article
|
TCF7L2 is a master regulator of insulin production and processing.
|
|
Academic Article
|
Enhancers: five essential questions.
|
|
Academic Article
|
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells.
|
|
Academic Article
|
Early-life physical activity reverses metabolic and Foxo1 epigenetic misregulation induced by gestational sleep disturbance.
|
|
Academic Article
|
Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice.
|
|
Academic Article
|
Regulation of MEIS1 by distal enhancer elements in acute leukemia.
|
|
Academic Article
|
Beyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolution.
|
|
Academic Article
|
A common genetic variant within SCN10A modulates cardiac SCN5A expression.
|
|
Academic Article
|
Comparative genomic analysis as a tool for biological discovery.
|
|
Academic Article
|
PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway.
|
|
Academic Article
|
HIF1a Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes.
|
|
Academic Article
|
Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders.
|
|
Academic Article
|
Probing chromatin landscape reveals roles of endocardial TBX20 in septation.
|
|
Academic Article
|
Editorial.
|
|
Academic Article
|
DNA methylation in lung cells is associated with asthma endotypes and genetic risk.
|
|
Academic Article
|
Reducing mitochondrial reads in ATAC-seq using CRISPR/Cas9.
|
|
Academic Article
|
Spatiotemporal distribution of different extracellular polymeric substances and filamentation mediate Xylella fastidiosa adhesion and biofilm formation.
|
|
Academic Article
|
A promoter interaction map for cardiovascular disease genetics.
|
|
Academic Article
|
Tbx20 Is Required in Mid-Gestation Cardiomyocytes and Plays a Central Role in Atrial Development.
|
|
Academic Article
|
Transfer RNA genes in the cap-oxil region of yeast mitochondrial DNA.
|
|
Academic Article
|
TCF7L2 (Transcription Factor 7-Like 2) Regulation of GATA6 (GATA-Binding Protein 6)-Dependent and -Independent Vascular Smooth Muscle Cell Plasticity and Intimal Hyperplasia.
|
|
Academic Article
|
Gene therapy for pathologic gene expression.
|
|
Academic Article
|
Identification of atrial fibrillation associated genes and functional non-coding variants.
|
|
Academic Article
|
Transcriptional Patterning of the Ventricular Cardiac Conduction System.
|
|
Academic Article
|
Advancing human health in the decade ahead: pregnancy as a key window for discovery: A Burroughs Wellcome Fund Pregnancy Think Tank.
|
|
Academic Article
|
Altered Enhancer and Promoter Usage Leads to Differential Gene Expression in the Normal and Failed Human Heart.
|
|
Academic Article
|
Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma.
|
|
Academic Article
|
Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression.
|
|
Academic Article
|
Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua.
|
|
Academic Article
|
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.
|
|
Academic Article
|
Establishment of human induced trophoblast stem-like cells from term villous cytotrophoblasts.
|
|
Academic Article
|
Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries.
|
|
Academic Article
|
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.
|
|
Academic Article
|
African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans.
|
|
Concept
|
Obesity, Metabolically Benign
|
|
Concept
|
Forkhead Box Protein O1
|
|
Concept
|
Alpha-Ketoglutarate-Dependent Dioxygenase FTO
|
|
Concept
|
Zinc Finger Protein GLI1
|
|
Concept
|
Wnt-5a Protein
|
|
Concept
|
Homeobox Protein Nkx-2.5
|
|
Concept
|
Myeloid Ecotropic Viral Integration Site 1 Protein
|
|
Concept
|
CCCTC-Binding Factor
|
|
Concept
|
Poly-ADP-Ribose Binding Proteins
|
|
Concept
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NAV1.5 Voltage-Gated Sodium Channel
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Concept
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NAV1.8 Voltage-Gated Sodium Channel
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Concept
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Clustered Regularly Interspaced Short Palindromic Repeats
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Concept
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CRISPR-Cas Systems
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Academic Article
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Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing.
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Academic Article
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Single cell profiling at the maternal-fetal interface reveals a deficiency of PD-L1+?non-immune cells in human spontaneous preterm labor.
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Academic Article
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A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes.
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Academic Article
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Splicing across adipocyte differentiation is highly dynamic and impacted by metabolic phenotype.
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Academic Article
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Mechanosensitive super-enhancers regulate genes linked to atherosclerosis in endothelial cells.
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Academic Article
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Dietary macronutrient composition impacts gene regulation in adipose tissue.
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Academic Article
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Paternal dietary macronutrient balance and energy intake drive metabolic and behavioral differences among offspring.
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